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Image Search Results
Journal: Pharmaceutical Research
Article Title: Assessing Dose-Exposure–Response Relationships of Miltefosine in Adults and Children using Physiologically-Based Pharmacokinetic Modeling Approach
doi: 10.1007/s11095-023-03610-0
Figure Lengend Snippet: Input Parameters for Miltefosine PBPK Model Simulations in Simcyp Human Simulator
Article Snippet: Finally, the miltefosine concentration profile in PBMCs was predicted using the
Techniques: Binding Assay, Molecular Weight, Permeability, Formulation, Activity Assay
Journal: The AAPS Journal
Article Title: Are Physiologically Based Pharmacokinetic Models Reporting the Right C max ? Central Venous Versus Peripheral Sampling Site
doi: 10.1208/s12248-015-9796-7
Figure Lengend Snippet: Current full-PBPK model in Simcyp with schematic representation of the peripheral sampling site model. The term Conc. fraction represents the fraction applied to each tissue concentration in the model
Article Snippet: The model described herein utilises the tissue concentration profiles predicted by the
Techniques: Sampling, Concentration Assay